| 產品編號 | bsm-2068M |
| 英文名稱 | Mouse Anti-Methamphetamine(4D2) antibody |
| 中文名稱 | 甲基苯丙胺（冰毒）單克隆抗體 |
| 別 名 | d-Desoxyephedrine hydrochloride; d-N; α-Dimethylphenethylamine hydrochloride; Methylamphetamine hydrochloride; METH. |
| 產品類型 | 小分子抗體 |
| 研究領域 | 藥物及化合物 |
| 抗體來源 | Mouse |
| 克隆類型 | Monoclonal |
| 克 隆 號 | 4D2 |
| 交叉反應 | (predicted: Methamphetamine) |
| 產品應用 | ELISA=1:5000-10000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理論分子量 | .18569kDa |
| 性 狀 | Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated Methamphetamine |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein G |
| 緩 沖 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事項 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 產品介紹 |
Methamphetamine (METH) is closely related chemically to amphetamine (AMPH). METH is a potent central nervous system stimulant with additional peripheral sympathomimetic effects. METH and AMPH have been used clinically in the treatment of obesity, minimal brain dysfunction, narcolepsy, depression and to counter fatigue. They are also subjected to widespread abuse. METH is an indirect agonists. It causes the release of newly synthesized norepinephrine and dopamine and it blocks the re uptake of these transmitters from the synapse. This can lead to an increase in the concentration of catecholamines in the synapse as well as an overall increase in catecholaminergic activity in the brain. The mechanism of METH induced neurotoxicity for all monoaminergic cell types may lie primarily with the dopaminergic system in the striatum. It may also lie with the interaction between METH induced release of dopamine and its ability to inhibit monoamine oxidase. 抗甲基安非他明抗體 過量的使用冰毒可導致急性中毒。嚴重者出現精神混亂、性欲亢進、焦慮、煩躁、幻覺狀態。長期濫用可造成慢性中毒、體重下降、消瘦、潰瘍、膿腫、指甲脆化和夜間磨牙。靜脈注射方式濫用者可引起各種感染合并癥；包括肝炎、細菌性心內膜炎、敗血癥和艾滋病等。 |
| 1、抗體溶解方法 | |
| 2、抗體修復方式 | |
| 3、常用試劑的配制 | |
| 4、免疫組化操作步驟 | |
| 5、免疫組化問題解答 | |
| 6、Western Blotting 操作步驟 | |
| 7、Western Blotting 問題解答 | |
| 8、關于肽鏈的設計 | |
| 9、多肽的溶解與保存 | |
| 10、酶標抗體效價測定程序 | |
